Doripenem is a potent antibiotic used to treat a variety of bacterial infections. However, during the manufacturing process, impurities may be generated, which can affect the quality and safety of the final product. These impurities can be related to starting materials, by-products, or degradation products and must be carefully monitored and controlled to ensure the purity and efficacy of the drug. Analytical methods such as HPLC and GC are used to detect and quantify these impurities.