Etravirine Impurities are the by-products or contaminants that may be present in Etravirine drug substance or drug product. These impurities can affect the quality, safety, and efficacy of Etravirine. It is important to identify, characterize, and control these impurities during the manufacturing process to ensure the quality of the final product. Different analytical techniques are used to detect and quantify these impurities. The International Conference on Harmonisation (ICH) provides guidelines for the