Fluocinolone is a synthetic corticosteroid used for the treatment of various skin conditions. However, it may contain impurities that can affect its quality and safety. These impurities can be formed during the manufacturing process or due to storage conditions. Some common Fluocinolone impurities include 6α-hydroxyfluocinolone acetonide, 6β-hydroxyfluocinolone acetonide, and 6α-hydroxy