Gadobutrol Impurities refer to any foreign substances or unwanted chemical compounds that may be present in a sample of Gadobutrol, which is a contrast agent used in medical imaging procedures. These impurities can affect the quality, safety, and efficacy of the final product, and therefore, it is essential to identify and control them during the manufacturing process. Various analytical techniques such as high-performance liquid chromatography (HPLC) and mass spectrometry (MS) are used to detect