Loteprednol is a corticosteroid used for the treatment of inflammation and pain in the eyes. However, during its production, various impurities may arise, which can potentially affect the purity, potency, and safety of the drug. These impurities may include process-related impurities, degradation products, and residual solvents. To ensure the quality and safety of the drug, regulatory authorities have set strict limits on the levels of these impurities in Loteprednol.