Loxapine is an antipsychotic medication used to treat symptoms of schizophrenia. However, during the manufacturing process, impurities may be introduced into the drug product. These impurities can affect the safety, efficacy, and quality of the medication. Therefore, it is crucial to identify and control these impurities to ensure that the final product is safe and effective for patients. Impurities in loxapine can be analyzed and quantified using various techniques such as high-performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC-MS).