Metaraminol is a medication used to increase blood pressure in cases of low blood pressure. However, during the manufacturing process, impurities can be introduced into the drug substance. These impurities can affect the safety and efficacy of the medication, and therefore, it is important to monitor and control their levels. Some common metaraminol impurities include related substances, residual solvents, and heavy metals. Analytical methods such as liquid chromatography and mass spectrometry are used to detect and quantify these impurities.