Methadol is a synthetic opioid used as an analgesic and for the treatment of opioid addiction. However, it is important to monitor the presence of impurities in Methadol as they can affect its potency and safety. Impurities can arise from the synthesis process, degradation, or storage conditions. Common impurities include related compounds, residual solvents, and heavy metals. Accurate impurity profiling and monitoring is crucial to ensure the quality and safety of Methadol for its intended use.