Piquindone is a synthetic compound that is used as an antipsychotic medication. Piquindone impurities are the unintended and unwanted substances that may be present in piquindone due to the manufacturing process, storage, or handling. These impurities can affect the quality, purity, and safety of the drug product, and may also have adverse effects on the patient's health. Therefore, it is important to identify and control the levels of piquindone impurities to ensure the efficacy and safety of the drug product.