Polmacoxib is a non-steroidal anti-inflammatory drug that is used to relieve pain and inflammation associated with various medical conditions. However, during the manufacturing process, impurities may be introduced into the final product. These impurities can be harmful to human health and must be carefully monitored and controlled. Various analytical techniques are used to detect and quantify these impurities, and strict regulatory guidelines must be followed to ensure the safety and efficacy of the final product.