Riboflavin (vitamin B2) is a water-soluble vitamin that plays an important role in various metabolic processes in the body. However, during the manufacturing process of riboflavin, impurities may be introduced that can affect the quality, safety, and efficacy of the final product. These impurities can include residual solvents, heavy metals, and other organic and inorganic compounds. It is important to monitor and control these impurities to ensure the purity and safety of riboflavin for use in supplements, pharmaceuticals, and other applications.