Rifaximin is an antibiotic used to treat bacterial infections in the gut. However, during the manufacturing process, impurities may be introduced into the final product. These impurities can affect the purity, quality, and safety of the drug. Therefore, it is important to identify and quantify these impurities to ensure that the drug is safe and effective for patients. Various analytical techniques are used to detect and quantify rifaximin impurities, including high-performance liquid chromatography (HPLC) and gas chromatography-mass spectrometry (GC-MS).
