Rotigotine is a dopamine receptor agonist used to treat Parkinson's disease and restless leg syndrome. However, during the manufacturing process, impurities may form which can affect the purity and potency of the final product. These impurities can be potentially harmful and therefore need to be identified, characterized and controlled to ensure the safety and efficacy of the medication. Analytical methods such as HPLC and GC-MS are commonly used for the detection and quantification of Rotigotine impurities.