Segesterone is a synthetic progestin used in combination with estradiol to prevent pregnancy. However, like all chemicals, segesterone may contain impurities that can affect its safety and efficacy. These impurities can arise during the manufacturing process and may include residual solvents, heavy metals, and other organic and inorganic contaminants. Proper identification, quantification, and control of these impurities are essential to ensure the safety and quality of segesterone-based contraceptive products.