Displaying 13 results of Sibutramine Impurities Sibutramine is a drug used for obesity treatment. However, it has been found to be associated with several impurities that can cause adverse effects in patients. These impurities include N-desmethylsibutramine, benzylsibutramine, and N-di-desmethylsibutramine. These impurities can cause cardiovascular and neurological problems and can also have a negative impact on liver and kidney function. Therefore, it is important to monitor and control the presence of these impurities in sibutramine-containing products.