Displaying 12 results of Spironolactone Impurities Spironolactone is a medication used to treat conditions such as high blood pressure, heart failure, and edema. However, the drug can contain impurities that may be harmful to the human body. These impurities may include chemicals such as chlorothalonil and N-nitrosodimethylamine (NDMA), which have been linked to cancer and other health problems. It is important to carefully monitor the quality of spironolactone and any other medications to ensure they are safe for use.