Zonisamide is an anticonvulsant drug used to treat epilepsy and other neurological disorders. However, during the manufacturing process, impurities can be introduced into the final product. These impurities are unwanted and potentially harmful substances that can affect the purity, safety, and efficacy of the drug. Therefore, it is essential to identify, characterize, and control these impurities to ensure the quality of the final product. Various analytical techniques, such as HPLC, GC, and LC-MS, are used to detect and quantify zonisamide impurities.