[2'-D]guanosine monohydrate

2'-D-guanosine monohydrate, also known as 2'-deoxyguanosine monohydrate, is a nucleoside analog that is commonly used in molecular biology and biochemistry research. It is a modified form of guanosine that lacks the hydroxyl group at the 2' position on the ribose sugar, making it an ideal substrate for DNA synthesis. 2'-D-guanosine monohydrate is often used in the synthesis of oligonucleotides, which are short strands of DNA or RNA that are used in a variety of applications such as gene editing, genetic sequencing, and gene expression analysis. It is also used in the preparation of nucleotide analogs, which are molecules that mimic the structure of natural nucleotides and can be used as drugs or diagnostic tools. The chemical formula of 2'-D-guanosine monohydrate is C10H13N5O4, and its molecular weight is 283.24 g/mol. It is a white crystalline powder that is soluble in water and has a melting point of 230-234°C. In terms of safety, 2'-D-guanosine monohydrate is considered to be relatively non-toxic, although it may cause skin and eye irritation upon contact. As with any chemical, it should be handled with care and appropriate protective measures should be taken when working with it.