17β-Estradiol-16,16,17-d3 3-Benzoate

17β-Estradiol-16,16,17-d3 3-Benzoate is a stable isotopically labeled analog of 17β-estradiol, a naturally occurring hormone in humans and animals that plays a crucial role in the regulation of the reproductive system. This particular compound is commonly used in scientific research studies to investigate the biological effects of estradiol on various biological pathways and processes. The addition of three deuterium atoms on the molecule provides a method for researchers to trace the metabolic fate of estradiol in biological systems. This isotopically labeled compound can be used in pharmacokinetic studies to determine how the compound is absorbed, distributed, metabolized, and eliminated in vivo. As a benzoate ester, the compound is commonly used in formulations for transdermal drug delivery systems. This delivery method allows for the controlled release of the compound over a period of time, which enhances its therapeutic efficacy and minimizes side effects. In terms of chemical information, 17β-Estradiol-16,16,17-d3 3-Benzoate has a molecular formula of C26H27D3O4 and a molecular weight of 409.54 g/mol. It has a melting point range of 167-170 °C and a boiling point of 578.2 °C at 760 mmHg. Overall, 17β-Estradiol-16,16,17-d3 3-Benzoate is a valuable compound in scientific research and drug development due to its stability, isotopic labeling, and potential therapeutic applications.