5-Hydroxyindoleacetic acid-[13C6]

5-Hydroxyindoleacetic acid-[13C6] is a stable isotope-labeled form of the neurotransmitter serotonin metabolite 5-Hydroxyindoleacetic acid (5-HIAA). It is commonly used in research and clinical settings to study serotonin metabolism and to diagnose and monitor disorders related to serotonin dysfunction such as depression, anxiety, and schizophrenia. The stable isotope incorporation in the molecule allows for more accurate measurement of 5-HIAA levels in biological samples such as urine, plasma, and cerebrospinal fluid. By adding a known quantity of 5-Hydroxyindoleacetic acid-[13C6] to a sample and measuring the ratio of labeled to unlabeled 5-HIAA, the concentration of the neurotransmitter can be accurately determined. Additionally, 5-Hydroxyindoleacetic acid-[13C6] can be used in tracer studies to better understand the metabolic pathways of serotonin. By tracking the labeled molecule through various metabolic pathways, researchers can gain insights into the role of serotonin in various physiological processes and identify potential targets for therapeutic interventions. In terms of chemical information, 5-Hydroxyindoleacetic acid-[13C6] has a molecular weight of 209.19 g/mol and a molecular formula of C10H6D6NO4. It is stable under normal storage and handling conditions and is typically supplied as a dry powder or solution in various solvents such as water, ethanol, or acetonitrile.