6’-Carboxy Simvastatin-d6
| Product Name | 6’-Carboxy Simvastatin-d6 |
|---|---|
| Alternate Names | Simvastatin Stable Isotopes, Stable Isotopes of Simvastatin |
| CAT No. | CS-T-70464 |
| CAS No. | 1346604-34-9 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Simvastatin |
| Smileys | CCC(C([2H])([2H])[2H])(C(OC1CC(C(O)=O)C=C2C1C(CCC3CC(O)CC(O3)=O)C(C)C=C2)=O)C([2H])([2H])[2H] |
| Canonical Smiles | CCC(C)(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C(=O)O |
| InchIKey | XKRMLBJLSDIWTC-NPQYNQSCSA-N |
| Inchl | InChI=1S/C25H36O7/c1-5-25(3,4)24(30)32-20-11-16(23(28)29)10-15-7-6-14(2)19(22(15)20)9-8-18-12-17(26)13-21(27)31-18/h6-7,10,14,16-20,22,26H,5,8-9,11-13H2,1-4H3,(H,28,29)/t14-,16-,17+,18+,19-,20-,22-/m0/s1/i3D3,4D3 |
| IUPAC | (2R,4S,4aR,5S,6S)-4-[2,2-bis(trideuteriomethyl)butanoyloxy]-5-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-6-methyl-2,3,4,4a,5,6-hexahydronaphthalene-2-carboxylic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
6'-Carboxy Simvastatin-d6 is a deuterated form of 6'-carboxy simvastatin, which is a metabolite of simvastatin, a widely used cholesterol-lowering drug. The deuterium-labeled version is used in pharmacokinetic and metabolic studies to better understand the pathway of simvastatin metabolism in the human body.
Simvastatin works by inhibiting the enzyme HMG-CoA reductase, which is responsible for the production of cholesterol in the liver. This leads to a decrease in the levels of low-density lipoprotein (LDL) cholesterol, also known as "bad" cholesterol, in the blood.
6'-Carboxy Simvastatin-d6 is produced by the breakdown of simvastatin in the liver, and it is excreted in the urine. It is a potent inhibitor of the enzyme HMG-CoA reductase, but it is not used as a therapeutic agent due to its short half-life and limited efficacy in reducing cholesterol levels.
In summary, 6'-Carboxy Simvastatin-d6 is a useful tool in pharmacological research as it helps to elucidate the metabolic pathway of simvastatin in the body. Its chemical structure and properties make it an ideal compound for use in pharmacokinetic and metabolic studies.
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Related Compounds
Simvastatin hydroxy acid D6 ammonium salt | Simvastatin D3 Lactone | Simvastatin hydroxy acid D3 ammonium salt | Simvastatin D3 | Simvastatin 13C D3 | Simvastatin-D6 sodium salt | Simvastatin acid D3 | Simvastatin hydroxyl acid D6 Sodium salt | Simvastatin D6 Lactone | Simvastatin Acid D6 |