6-Carboxy Δ-5',4',5,6-Simvastatin D6
| Product Name | 6-Carboxy Δ-5',4',5,6-Simvastatin D6 |
|---|---|
| Alternate Names | Simvastatin Stable Isotopes, Stable Isotopes of Simvastatin |
| CAT No. | CS-T-70824 |
| CAS No. | 1346600-14-3 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Simvastatin |
| Smileys | CCC(C)(C)C(=O)OC1CC(=CC2=CCC(C(C12)CCC3CC(CC(=O)O3)O)C)C(=O)O |
| Canonical Smiles | CCC(C)(C)C(=O)OC1CC(=CC2=CCC(C(C12)CCC3CC(CC(=O)O3)O)C)C(=O)O |
| InchIKey | CGKWQIRKHPKYEV-YYGNBHKXSA-N |
| Inchl | InChI=1S/C25H36O7/c1-5-25(3,4)24(30)32-20-11-16(23(28)29)10-15-7-6-14(2)19(22(15)20)9-8-18-12-17(26)13-21(27)31-18/h7,10,14,17-20,22,26H,5-6,8-9,11-13H2,1-4H3,(H,28,29)/t14-,17+,18+,19-,20-,22-/m0/s1/i3D3,4D3 |
| IUPAC | (4S,4aR,5S,6S)-4-[2,2-bis(trideuteriomethyl)butanoyloxy]-5-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-6-methyl-3,4,4a,5,6,7-hexahydronaphthalene-2-carboxylic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
6-Carboxy Δ-5',4',5,6-Simvastatin D6 is a stable isotopic labeled form of Simvastatin, a cholesterol-lowering medication. Simvastatin is a member of the statin class of drugs, which works by inhibiting the enzyme HMG-CoA reductase, thereby reducing the production of cholesterol in the liver. It is prescribed to patients with high levels of cholesterol or triglycerides in their blood, as a preventative measure for cardiovascular disease.
6-Carboxy Δ-5',4',5,6-Simvastatin D6 is used as a reference standard for the quantification of Simvastatin and its metabolites in biological samples. It is also used in research studies to investigate the pharmacokinetics and pharmacodynamics of Simvastatin in the body. The isotopic label on the molecule allows for accurate measurement of the drug's metabolism and elimination rates.
The chemical formula of 6-Carboxy Δ-5',4',5,6-Simvastatin D6 is C26H31D6O7, with a molecular weight of 505.61 g/mol. It is a white to off-white powder that is soluble in dimethyl sulfoxide (DMSO), methanol, and ethanol. The compound has a melting point of 146-150°C and a purity of at least 98%.
In conclusion, 6-Carboxy Δ-5',4',5,6-Simvastatin D6 is a useful tool in the field of drug metabolism research. Its isotopic labeling provides accurate measurement of Simvastatin and its metabolites in biological samples, allowing for better understanding of the drug's pharmacokinetics and pharmacodynamics.
Get an Instant Quote
Related Compounds
Simvastatin hydroxy acid D6 ammonium salt | Simvastatin Acid D6 | Simvastatin D3 | Simvastatin acid D3 | Simvastatin D3 Lactone | Simvastatin-D6 sodium salt | Simvastatin 13C D3 | Simvastatin D6 Lactone | Simvastatin hydroxy acid D3 ammonium salt | Simvastatin hydroxyl acid D6 Sodium salt |