6-O-Methyl-d3-guanine

Product Name 6-O-Methyl-d3-guanine
Alternate Names Guanine Stable Isotopes, Stable Isotopes of Guanine
CAT No. CS-T-58247
CAS No. 50704-43-3
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Guanine
Smileys NC1=NC2=NC=NC2=C(N1)OC([2H])([2H])[2H]
Canonical Smiles COC1=NC(=NC2=C1NC=N2)N
InchIKey BXJHWYVXLGLDMZ-FIBGUPNXSA-N
Inchl InChI=1S/C6H7N5O/c1-12-5-3-4(9-2-8-3)10-6(7)11-5/h2H,1H3,(H3,7,8,9,10,11)/i1D3
IUPAC 6-(trideuteriomethoxy)-7H-purin-2-amine
Controlled No
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6-O-Methyl-d3-guanine is a modified nucleoside that is used in the study of RNA and DNA structures and functions. It is a deuterated form of 6-O-Methylguanine, which is a naturally occurring nucleoside that is found in tRNA and rRNA. The deuterium substitution in 6-O-Methyl-d3-guanine allows for its detection and identification in complex nucleotide mixtures using mass spectrometry. This modified nucleoside has been used in various studies to investigate the role of RNA modifications in various biological processes such as transcription, translation, and mRNA splicing. It has also been used in the synthesis of stable isotope-labeled RNA for studies involving NMR spectroscopy. The chemical structure of 6-O-Methyl-d3-guanine consists of a purine base (guanine) that is attached to a deoxyribose sugar molecule via a glycosidic bond. The methyl group is attached to the 6th position of the purine ring. The deuterium substitution in this compound replaces a hydrogen atom with a heavier isotope and does not significantly alter the chemical properties or reactivity of the molecule. In conclusion, 6-O-Methyl-d3-guanine is a valuable tool in RNA research and its chemical structure provides important insights into the role of RNA modifications in various biological processes.

Related Compounds

Guanine-13C5,15N5 | N7-[(2-Hydroxyethoxy)methyl)guanine-d4 | Guanine-15N5 | Guanine 13C3,15N2 | N7-(2-Hydroxyethyl)guanine-d4 | Guanine-4,8-13C2,7-15N |

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