7-(1-Methyl-2-hydroxyethyl)guanine-d7 (Major)

7-(1-Methyl-2-hydroxyethyl)guanine-d7 (Major) is a deuterated form of 7-(1-Methyl-2-hydroxyethyl)guanine (Major), a nucleoside analog that is used as an antiviral drug. Major is a synthetic compound that is structurally similar to guanine, a naturally occurring nucleoside that is a component of DNA and RNA. Major is used to treat infections caused by the herpes simplex virus (HSV), which can cause cold sores, genital herpes, and other infections. Major works by inhibiting the replication of the virus. It is incorporated into the viral DNA during replication, where it disrupts the normal base-pairing interactions and prevents the DNA from being properly copied. This ultimately leads to the death of the virus and a reduction in symptoms in the patient. The deuterated form of Major, 7-(1-Methyl-2-hydroxyethyl)guanine-d7, is used in research to study the metabolism and pharmacokinetics of the drug. Deuterium is a stable isotope of hydrogen that can be used to label molecules and track their movement in the body. By using deuterated forms of drugs, researchers can gain a better understanding of how the drug is metabolized and excreted, which can be useful in developing new treatments and improving existing ones. Overall, 7-(1-Methyl-2-hydroxyethyl)guanine-d7 (Major) is an important tool in the fight against viral infections and a valuable resource for researchers studying antiviral drugs.