Alvimopan-D7
| Product Name | Alvimopan-D7 |
|---|---|
| Alternate Names | Alvimopan Stable Isotopes, Stable Isotopes of Alvimopan |
| CAT No. | CS-O-11332 |
| CAS No. | 1261396-48-8 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Alvimopan |
| Smileys | C[C@](CCN(C[C@@H](C(NCC(O)=O)=O)C([2H])([2H])C(C([2H])=C1[2H])=C(C([2H])=C1[2H])[2H])C2)(C3=CC(O)=CC=C3)[C@H]2C |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Alvimopan-D7 is a deuterated form of Alvimopan, which is a selective antagonist of the μ-opioid receptor. It is used in the treatment of postoperative ileus (POI) in patients who have undergone a partial or total bowel resection. POI is a common complication that occurs following abdominal surgery, which causes a delay in the return of normal bowel function. Alvimopan-D7 works by blocking the μ-opioid receptors in the gastrointestinal tract, which can help speed up the recovery process.
Chemically, Alvimopan-D7 is a synthetic tetrapeptide that consists of four amino acids – L-alanine, D-phenylalanine, D-tryptophan, and L-lysine. The addition of deuterium atoms to the molecule does not change its chemical properties or mode of action, but it does provide a useful tool for pharmacokinetic studies.
Alvimopan-D7 is administered orally, and its effects last for approximately 24 hours. It is metabolized in the liver and excreted in the urine, with a half-life of around 10 hours. The recommended dose of Alvimopan-D7 is 12mg, taken 30 minutes before surgery, followed by 12mg twice daily for up to 7 days.
Overall, Alvimopan-D7 is a safe and effective treatment for postoperative ileus, with minimal side effects. However, it should only be used under the supervision of a qualified healthcare professional.
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Related Compounds
Alvimopan metabolite D7 (ADL08-0011), hydrochloride | Alvimopan D5 metabolite | Alvimopan D5 |