Amlodipine N-Lactoside

Product Name Amlodipine N-Lactoside
Alternate Names Amlodipine Impurities, Impurities of Amlodipine
CAT No. CS-P-03120
CAS No. 749864-27-5
Category Impurities
Stock IN-Stock
Mol. Wt. 733.16 g/mol
Mol. For. C₃₂H₄₅ClN₂O₁₅
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Amlodipine
Purity 95%
Therapeutic Anti-Hypertensives
Smileys O=C(C1=C(COCCNC2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O[C@@H]3[C@@H]([C@H]([C@H]([C@@H](CO)O3)O)O)O)O)O)NC(C)=C(C(OC)=O)C1C4=CC=CC=C4Cl)OCC
Controlled No
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Amlodipine N-Lactoside is a chemical compound that belongs to the family of dihydropyridine calcium channel blockers. It has been developed as a prodrug of amlodipine, which is one of the most widely used antihypertensive drugs globally. Amlodipine N-Lactoside is used to treat hypertension, angina, and other cardiovascular diseases. The compound works by blocking the influx of calcium ions into the smooth muscle cells of the blood vessels, leading to vasodilation and a reduction in blood pressure. Amlodipine N-Lactoside has several advantages over amlodipine. It has better solubility and bioavailability, which means that it can be absorbed more efficiently by the body, and therefore, it requires a lower dose for therapeutic effect. Additionally, Amlodipine N-Lactoside has fewer side effects than amlodipine, such as headache, flushing, and edema. The chemical structure of Amlodipine N-Lactoside is a lactose conjugate of amlodipine, with the lactose moiety acting as a prodrug carrier. After oral administration, the lactose moiety is cleaved by enzymes in the intestine, releasing amlodipine into the bloodstream. This process leads to a slower and more prolonged release of amlodipine, resulting in a more stable and long-lasting therapeutic effect. In conclusion, Amlodipine N-Lactoside is a promising prodrug of amlodipine that offers better solubility, bioavailability, and fewer side effects. It has the potential to improve the treatment of hypertension and other cardiovascular diseases.

Related Compounds

Amlodipine Impurity 61 | Amlodipine EP Impurity D Oxalate Salt | Amlodipine Impurity 32 | N-Fomyl Amlodipine | Amlodipine Related Compound A | Amlodipine Impurity 19 | Amlodipine Nitroso Impurity | Phthaloyl Amlodipine Dimethyl Ester | Deschloro Amlodipine | N-Nitroso Amlodipine | Atorvastatin Amlodipine Dimer | Amlodipine Galactose Adduct | Dimethoxy Impurity Deschloro Amlodipine | Desmethyl Amlodipine | Amlodipine Impurity 38 | Amlodipine EP Impurity D HCl | Amlodipine Impurity 34 | Amlodipine EP Impurity B | Amlodipine EP Impurity E Maleate | Amlodipine EP Impurity E | Amlodipine N-Galactose | Amlodipine aminoethyl | Amlodipin EP Impurity D | Amlodipine EP Impurity A | Amlodipine EP Impurity G | Amlodipine Impurity F Maleate | Amlodipine EP Impurity H | Amlodipine Impurity 9 | N-Nitroso Amlodipine EP Impurity F | Amlodipine Mannitol Adduct Acetate Salt | Amlodipine Impurity 8 | R-Amlodipine hemipentahydrate | Amlodipine Impurity | Amlodipine Mannitol Adduct HCl Salt | Amlodipine Besylate Impurity D Besylate salt | Dehydro Amlodipine N-Oxide | Amlodipine Azido Impurity | Amlodipine Aspartic Acid Impurity | Amlodipine morpholine impurity | Amlodipine EP Impurity F | Di-acid Amlodipine | Amlodipine Impurity 29 | Amlodipine orotate | Hydroxyethyl phthalyl amlodipine | Amlodipine EP Impurity C | Atorvastatin-Amlodipine Adduct | Amlodipine Methyl Ester | Amlodipine For Peak Identification | Amlodipine Lactose adduct | Amlodipine Mannitol Adduct | Amlodipine Impurity 25 | R-Amlodipine Besilate |

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