Atomoxetine-D5

Atomoxetine-D5 is a deuterated form of Atomoxetine, a selective norepinephrine reuptake inhibitor (SNRI) that is used to treat attention deficit hyperactivity disorder (ADHD). Atomoxetine-D5 is chemically identical to Atomoxetine, but five deuterium atoms have been substituted for five hydrogen atoms in its molecular structure. This isotopic labeling allows for more precise analysis of the drug's pharmacokinetics and metabolism in the body. Atomoxetine-D5 works by increasing the levels of norepinephrine in the brain, which helps to improve attention and reduce impulsivity and hyperactivity in people with ADHD. It is typically taken orally once or twice a day, with or without food, and the dosage is based on the individual's weight and response to the medication. In terms of chemical information, Atomoxetine-D5 has a molecular formula of C17H19NO2D5 and a molecular weight of 307.45 g/mol. It is a white to off-white powder that is soluble in water and ethanol. Atomoxetine-D5 undergoes extensive metabolism in the liver, primarily through the cytochrome P450 enzyme system, and its metabolites are excreted in the urine. It has a half-life of approximately 5 hours in adults, but this can vary depending on factors such as age, gender, and liver function. Overall, Atomoxetine-D5 is a valuable tool for researchers studying the pharmacokinetics and metabolism of Atomoxetine, and it has the potential to improve our understanding of how this drug works in the body.