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- Synonyms:Dolutegravir Enantiomer Impurity
- Chemical Name:(3R,7S)-N-[(2,4-difluorophenyl)methyl]-11-hydroxy-7-methyl-9,12-dioxo-4-oxa-1,8-diazatricyclo[8.4.0.03,8]tetradeca-10,13-diene-13-carboxamide
- Application Notes:"Dolutegravir SR Isomer is an isomeric derivative of Dolutegravir, a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector. Dolutegravir SR Isomer."
- Product Category:Dolutegravir Impurities
Dolutegravir SR Isomer is identified by CAS No. 1309560-49-3 and is chemically known as Dolutegravir Enantiomer Impurity, IUPAC Name: (3R,7S)-N-[(2,4-difluorophenyl)methyl]-11-hydroxy-7-methyl-9,12-dioxo-4-oxa-1,8-diazatricyclo[8.4.0.03,8]tetradeca-10,13-diene-13-carboxamide.
Dolutegravir SR Isomer is provided with comprehensive characterization data in accordance with regulatory guidelines. It is suitable for use in analytical method development, method validation (AMV), Quality Control (QC) applications for Abbreviated New Drug Applications (ANDA) and commercial production of Dolutegravir.
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Dolutegravir SR Isomer
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