ent-Ezetimibe

Product Name ent-Ezetimibe
Alternate Names Ezetimibe Impurities, Impurities of Ezetimibe
CAT No. CS-T-75143
CAS No. 1376614-99-1
Category Impurities
Stock IN-Stock
Mol. Wt. 409.43 g/mol
Mol. For. C₂₄H₂₁F₂NO₃
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Ezetimibe
Purity Not less than 90 %
Therapeutic Anti-Hyperlipidemics
Smileys O[C@@H](C1=CC=C(F)C=C1)CC[C@H]2[C@H](C3=CC=C(O)C=C3)N(C4=CC=C(F)C=C4)C2=O
Canonical Smiles C1=CC(=CC=C1C2C(C(=O)N2C3=CC=C(C=C3)F)CCC(C4=CC=C(C=C4)F)O)O
InchIKey OLNTVTPDXPETLC-ZRBLBEILSA-N
Inchl InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m0/s1
IUPAC (3S,4R)-1-(4-fluorophenyl)-3-[(3R)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one
Controlled No
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Ent-Ezetimibe is a medication used to lower cholesterol levels in the body. It belongs to a class of drugs known as cholesterol absorption inhibitors. The drug works by blocking the absorption of cholesterol from the small intestine, thereby reducing the amount of cholesterol that enters the bloodstream. Ent-Ezetimibe is a stereoisomer of the commonly used medication Ezetimibe. It has the same chemical formula and structure as Ezetimibe, but the orientation of the atoms in the molecule is different. This difference in orientation gives ent-Ezetimibe slightly different pharmacological properties than Ezetimibe. The chemical name for ent-Ezetimibe is (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one. The molecular formula is C24H21F2NO3 and the molecular weight is 409.4 g/mol. Ent-Ezetimibe is typically administered orally as a tablet. The recommended dose is 10 mg once daily, with or without food. The drug is metabolized in the liver and excreted in the feces. Overall, ent-Ezetimibe is a safe and effective medication for reducing cholesterol levels in the body. It is important to note that ent-Ezetimibe should not be used as a substitute for a healthy diet and exercise. It is best to consult with a healthcare provider to determine if ent-Ezetimibe is right for you.

Related Compounds

Ezetimibe Related Impurity 7 | Ezetimibe Benzyl Diol Impurity | Ezetimibe 2-Fluoro Hydroxy impurity | Methyl 5-(4-Fluorophenyl)-(5S)-hydroxypentanoate | Ezetimibe Lactone Impurity | RRR-Ezetimibe+SSS-Ezetimibe (Diastereomer mixture) | Benzylated Ezetimibe | Ezetimibe (3S,4S,3'R)-Isomer | Ezetimibe Trihydroxy Impurity | SSR-Ezetimibe | Ezetimibe (3R,4R,3'R)-Isomer | Ezetimibe Dides fluoro impurity | Ezetimibe Triol Impurity | Ezetimibe Diol Impurity | RSR Ezetimibe | Ezetimibe Impurity 10 | Ezetimibe Impurity 17 | Ezetimibe Impurity 18 | Ezetimibe Impurity 11 | Ezetimibe Impurity B | Ezetimibe 2-Fluoro impurity | Ezetimibe Benzyl Impurity (MBZT-2) | Ezetimibe Impurity 1 ((3'S,3R,4S)-Desfluoro Ezetimibe) | Ezetimibe Impurity C | N-Nitroso Ezetimibe Impurity | O-Fluoroaniline isomer of Ezetimibe | m-Fluoroaniline isomer of Ezetimibe | Ezetimibe Didesfluro impurity | Ezetimibe O-trimethylsilyl O-benzyl Impurity | Ezetimibe Deprotected Impurity | Ezetimibe Impurity 25 | Ezetimibe impurity (3-[5-(4-Fluoro-phenyl)-5-(R)-hydroxy-pentanoyl]-4-(S)-phenyl-oxazolidin-2-one) | Ezetimibe Ring-opening Dehydrate Impurity | Ezetimibe tetrahydropyran analog | Ezetimibe Lactam Cleaved Alcohol | Ezetimibe ring open impurity | O-Fluorobenzene isomer of Ezetimibe | Ezetimibe Diacid | Ezetimibe Impurity 15 | Benzyl Ezetimibe ether | Ezetimibe Azetidinone Ring opened impurity | Ezetimibe Desfluoro impurity |

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