N-Methyl Pemetrexed
| Product Name | N-Methyl Pemetrexed |
|---|---|
| Alternate Names | Pemetrexed Impurities, Impurities of Pemetrexed |
| CAT No. | CS-T-34609 |
| CAS No. | 869791-42-4 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 441.4 g/mol |
| Mol. For. | C21H23N5O6 |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Pemetrexed |
| Therapeutic | Anti-Cancer / Oncology |
| Smileys | CN1C2=C(C(=CN2)CCC3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O)C(=O)N=C1N |
| Canonical Smiles | CN1C2=C(C(=CN2)CCC3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O)C(=O)N=C1N |
| InchIKey | JKULRGFPYBAJTE-AWEZNQCLSA-N |
| Inchl | InChI=1S/C21H23N5O6/c1-26-17-16(19(30)25-21(26)22)13(10-23-17)7-4-11-2-5-12(6-3-11)18(29)24-14(20(31)32)8-9-15(27)28/h2-3,5-6,10,14,23H,4,7-9H2,1H3,(H,24,29)(H,27,28)(H,31,32)(H2,22,25,30)/t14-/m0/s1 |
| IUPAC | (2S)-2-[[4-[2-(2-amino-1-methyl-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
N-Methyl Pemetrexed is a chemotherapy drug used to treat certain types of cancer, including mesothelioma and non-small cell lung cancer. It works by inhibiting the process of DNA synthesis, which slows down the growth and spread of cancer cells. This medication is a modified form of Pemetrexed, which was approved by the FDA in 2004.
N-Methyl Pemetrexed is available in the form of a powder that is reconstituted for intravenous use. The dosage and frequency of administration depend on the patient's condition and response to treatment. It is typically administered by a healthcare professional in a clinical setting.
Chemically, N-Methyl Pemetrexed is a folate antimetabolite that targets multiple enzymes involved in purine and pyrimidine synthesis. It inhibits the activity of thymidylate synthase, dihydrofolate reductase, and glycinamide ribonucleotide formyltransferase, which are essential for DNA synthesis. This results in arrested cell division and ultimately leads to cancer cell death.
Like any medication, N-Methyl Pemetrexed is associated with certain side effects, such as nausea, vomiting, diarrhea, fatigue, and decreased appetite. Patients may also experience bone marrow suppression, which can increase the risk of infection and bleeding. It is important to inform healthcare providers of any side effects experienced during treatment. Overall, N-Methyl Pemetrexed is an important chemotherapy drug that has helped many patients in their fight against cancer.
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Related Compounds
Pemetrexed Alanine Impurity | Pemetrexed Alpha-hydroxy lactum isomers 2 | Pemetrexed EP Impurity E | Tris Pemetrexed | Pemetrexed Disodium – D-Isomer | Pemetrexed Impurity 33 | Pemetrexed Monomethyl Ester 1 | Pemetrexed Alpha-hydroxy lactum | Pemetrexed opened Ring keto amide | Pemetrexed epoxy hemiaminal | Pemetrexed Impurity 2 | Pemetrexed Keto impurity di sodium salt | Pemetrexed disodium Impurity A | Pemetrexed EP Impurity B | Pemetrexed-1-methyl Ester | Pemetrexed Impurity 29 | Pemetrexed Monomethyl Ester 2 | Pemetrexed Impurity 28 | Pemetrexed Nitroso Impurity 2 | Pemetrexed Impurity 42 | Pemetrexed Impurity 20 | Pemetrexed Impurity 32 | N-nitroso Pemetrexed | Pemetrexed EP Impurity C | Pemetrexed Keto impurity isomers 2 | Pemetrexed Impurity Mixture (Impurities A and D) | Pemetrexed PMT-1 impurity | Pemetrexed Impurity 24 | Pemetrexed Diethyl Ester | Pemetrexed EP Impurity D | Pemetrexed Nitroso Impurity 3 | Pemetrexed Impurity A | Pemetrexed Impurity 36 | Pemetrexed Keto impurity (Mixture of isomers) | Diethyl ((S)-4-amino-5-ethoxy-5-oxopentanoyl)-L-glutamate | Pemetrexed Glutamide Impurity | Pemetrexed Dimethyl Ester | Pemetrexed EP Impurity B and Impurity C mixture |