N-Nitroso-L-(azetidine-d5)-2-carboxylic Acid
Also known as: - Nitrosamine Impurities or nitrosamine impurities of -| Product Name | N-Nitroso-L-(azetidine-d5)-2-carboxylic Acid |
|---|---|
| Alternate Names | - Stable Isotopes, Stable Isotopes of - |
| CAT No. | CS-T-94540 |
| CAS No. | 30248-47-6 (Unlabelled) |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | 135.13 g/mol |
| Mol. For. | C4HD5N2O3 |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | - |
| Controlled | No |
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N-Nitroso-L-(azetidine-d5)-2-carboxylic Acid (d5-NO-ACA) is a stable isotopically labeled derivative of N-Nitroso-L-(azetidine-2-carboxylic acid), which is a potent carcinogenic agent. d5-NO-ACA is used as an internal standard for analyzing NO-ACA in biological samples. This compound is used in the study of the mechanism of nitrosation and carcinogenicity of NO-ACA. The labeled compound is useful for quantitative analysis of NO-ACA in biological samples such as urine and blood.
NO-ACA is a potent carcinogen that has been shown to induce tumors in animal models. This compound is formed by the reaction of nitrite with the amino acid proline. NO-ACA is believed to be involved in the formation of nitrosamines, which are known to be carcinogenic. The mechanism of action of NO-ACA is not well understood, but it is believed to be involved in the production of DNA adducts and the inhibition of DNA repair mechanisms.
The chemical formula of d5-NO-ACA is C5H4D5N3O3. It has a molecular weight of 176.15 g/mol. The compound has a melting point of 203-205°C and a boiling point of 446.5°C. d5-NO-ACA is soluble in water and ethanol. The compound should be stored at -20°C and protected from light. It is important to handle the compound with caution as it is a potential carcinogen.
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Related Compounds
Azilsartan Medoxomil-D5 | N-Acetylneuraminic Acid Methyl Ester-d3 | Di-β-carbethoxyethyl-d8-methylamine | rac-cis-N-Desmethyl Sertraline-d3 Hydrochloride | rac 1-Oleoyl-2-linolenoyl-3-chloropropanediol-d5 | Defluoro Hydroxy AM-694-d4 | N-Nitrosoguvacine-2,2,5,5-D4 | p-Tyramine-d4 Hydrochloride (ethyl-D4) | Lincomycin B-d3 Hydrochloride | N-Nitrosobis(2-hydroxypropyl)amine-d12 | Dithio-2,2'-bis(N-methylbenzamide)-d6 | Hexahydro-1,3-isobenzofurandione-d8 | Niraparib 13C6 | Linoleoyl Carnitine (N-methyl-D3) | Sulfo-NHS-LC-Biotin-D10 | Uvinul A Plus-d4 | N-(Acetyl-d3)-S-(2-carboxyethyl)-L-cysteine Bis(dicyclohexylamine) Salt | tert-Butyl 3-((((R)-1-Amino-1-oxobutan-2-yl)amino)methyl)hexanoate-d7 | Almotriptan-D16 | Terbuthylazine-13C4 | C16-Ceramide-13C2,d2 | Ramipril Isopropyl-d3 Ester | Ethyl-5-(4-methoxy-d3-2,3,6-trimethylphenyl)-3-methyl-2,4-pentadienoate(cis/trans Mixture) | C-α-NAC Trimethoprim-d3 | Gamma-Hydroxybutyric acid glucuronide-d6 | RVX 208-d4 | Lenacil-d4 | Meldrum’s Acid-13C3 | L-Iditol-d8 | Benzaldehyde-6-d, 4,5-dihydroxy | SN-38 Glucuronide-13C3 | N-Methyl-1H-imidazole-1-carboxamide-d3 | Diethyl Itaconate-13C5 | N,N-Dimethyl-5-(phenylmethoxy)-1H-indole-3-ethan-a,a,b,b-d4-amine | Avatrombopag-D8 Hydrochloride | Octahydro-6-(phenylmethyl)-1H-Pyrrolo[3,4-b]pyridine-d4 | Chromonar-d10 Hydrochloride | DL-Cysteine-3,3-d2 | p-Methoxybenzyl O6-(2-Hydroxypropyl)-2’-deoxyguanosine-d3 | methyl (6-benzoyl-1-methyl-d3-1H-benzo[d]imidazol-2-yl)(methyl-d3)carbamate | Uridine 5′-Monophosphomorpholidate 4-Morpholine-N,N′-dicyclohexylcarboxamidine Salt-13C, 15N2 | L-threo-a-Phenyl-2-piperidineacetamide-d10 | rac-1,2-Dioctanoyl-3-Chloropropanediol-d5 | Diphenhydramine-d3 Dimer | N-Iodoacetyltyramine-d4 | Fructose-glutamic Acid-D5 | Formaldehyde 2,4-Dinitrophenylhydrazone-13C | N-Nitrosobenzylmethyl-d3-amine | N-Benzyl Di-O-TBS Epinephrine-d3 | Serotonin-13C215N Hydrochloride | Des-(Cyclohexa-2,5-dien-1-one) Androsta-(E)-3-oxobut-1-en-1-yl-2,3,4-13C3) | N-[1-(3’-Benzyloxyphenyl)ethyl]-N-(methyl-d3)-O-ethylcarbamate | Chenodeoxycholic Acid-d7 (Major) | Methyl-d3-N-methylanthranilate | N1-Acetyl Triethylenetetramine D4 | Tetrahydro-4-pyrone-d8 | N-Nitroso Morpholine-D8 (1000µg/mL) in Methanol | N-Nitrosoethylmethylamine-13C3 | Aminopyralid-13C2,15N | Rebaudioside B (13CD2) | N-Nitrosopendimethalin-d4 | Cylindrospermopsin-13C,15N2 | Boc-N-(methyl-d3)-L-alanine-d4 | Ethyl α-Ketoisocaproate-d7 | K777 Hydrochloride-d8 | Tetraethylthiourea-d10 | Dehydro Lercanidipine-d3 | N,N’-Bis-Boc-1-guanylpyrazole-13C,15N2 | N-(1-(Adamantan-1-yl)ethyl-d4)hydroxylamine | Desfluoro Pimozide-d5 |