N-nitroso Sertraline-13CD4 15N

N-nitroso Sertraline-13CD4 15N is a chemical compound that is commonly used as a research tool in the field of biochemistry. It is a derivative of Sertraline, which is an antidepressant medication that is used to treat major depressive disorders, anxiety disorders, and obsessive-compulsive disorders. This compound is created by introducing a nitroso group (NO) onto one of the nitrogen atoms in the Sertraline molecule. Additionally, it has four deuterium atoms (D) and fifteen nitrogen atoms (N) in its structure. The primary use of N-nitroso Sertraline-13CD4 15N is in studies regarding the metabolism and effects of Sertraline in the human body. The isotopic labeling of this compound allows researchers to track its movement and interactions within the body. This information can provide valuable insights into the pharmacokinetics and pharmacodynamics of Sertraline, which can help improve the effectiveness and safety of this medication. Chemically, the introduction of the nitroso group onto the Sertraline molecule alters its reactivity and properties. Nitroso compounds are known to be highly reactive towards a variety of biological molecules, including thiols and amines. This reactivity can lead to the formation of adducts between N-nitroso Sertraline-13CD4 15N and biological molecules, which can interfere with cellular processes. Therefore, understanding the chemical properties of this compound is important for both its use as a research tool and for the safety of individuals taking Sertraline.