N-nitroso Sertraline-D3 15N

N-Nitroso Sertraline-D3 15N is a chemical compound that is commonly used in medical research and drug development. It is a derivative of Sertraline, a selective serotonin reuptake inhibitor (SSRI) commonly used as an antidepressant. The compound is labeled with deuterium and nitrogen-15 isotopes, which make it useful for tracking the metabolism and pharmacokinetics of Sertraline in vivo. N-Nitroso Sertraline-D3 15N is a potent nitrosating agent, which means it can react with amines and amides to form N-nitrosamines. This reaction is of interest in cancer research, as N-nitrosamines are known to be carcinogenic. The compound has also been shown to induce DNA damage and cell death in vitro, which may have implications for its use as a chemotherapeutic agent. In addition to its potential applications in cancer research, N-Nitroso Sertraline-D3 15N is also useful for studying the metabolism and pharmacokinetics of Sertraline. By labeling the drug with isotopes, researchers can track its absorption, distribution, metabolism, and excretion in vivo. This information can be used to optimize dosing regimens and improve the efficacy and safety of the drug. Overall, N-Nitroso Sertraline-D3 15N is a valuable tool for medical research and drug development, with potential applications in cancer research and the optimization of Sertraline therapy.