N-Nitrosodiisobutylamine-d4

N-Nitrosodiisobutylamine-d4 is a stable isotope-labeled analog of N-Nitrosodiisobutylamine (NDIBA), a potent carcinogenic compound that is commonly found in tobacco smoke, rubber products, and other industrial processes. This isotopically labeled compound is used as an internal standard in analytical chemistry applications, particularly in gas chromatography-mass spectrometry (GC-MS) analyses of NDIBA in biological and environmental samples. The chemical structure of N-Nitrosodiisobutylamine-d4 is similar to that of NDIBA, with the exception of four deuterium atoms that replace four hydrogen atoms in the molecule. This labeling strategy allows for accurate quantification of NDIBA in complex matrices by providing a reliable reference signal that is not affected by matrix effects or instrument variability. The potential health hazards associated with NDIBA make it important to accurately measure its levels in various samples, as well as to investigate its sources and pathways of formation. The use of N-Nitrosodiisobutylamine-d4 as an internal standard in GC-MS analyses provides a reliable and accurate tool for researchers to better understand the exposure and potential health risks associated with NDIBA.