Pemetrexed Impurity A
| Product Name | Pemetrexed Impurity A |
|---|---|
| Alternate Names | Pemetrexed Impurities, Impurities of Pemetrexed |
| CAT No. | CS-O-31666 |
| CAS No. | 137281-39-1 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 298.30 g/mol |
| Mol. For. | C₁₅H₁₄N₄O₃ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Pemetrexed |
| Therapeutic | Anti-Cancer / Oncology |
| Canonical Smiles | C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)O |
| InchIKey | AIZPFZIKHIJCQX-UHFFFAOYSA-N |
| Inchl | InChI=1S/C15H14N4O3/c16-15-18-12-11(13(20)19-15)10(7-17-12)6-3-8-1-4-9(5-2-8)14(21)22/h1-2,4-5,7H,3,6H2,(H,21,22)(H4,16,17,18,19,20) |
| IUPAC | 4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Pemetrexed Impurity A is a chemical compound that is used as a reference standard for the testing of pemetrexed, an antifolate chemotherapy drug used for the treatment of various types of cancer, including mesothelioma, lung cancer, and breast cancer. Pemetrexed Impurity A is a known impurity of pemetrexed, and its presence can affect the quality and efficacy of the drug. It is therefore important to monitor and control the levels of impurities during the manufacturing process of pemetrexed to ensure the safety and effectiveness of the drug.
The chemical formula of Pemetrexed Impurity A is C20H21N7O7, and its molecular weight is 479.43 g/mol. It is a white to off-white crystalline powder that is soluble in water and methanol. Pemetrexed Impurity A is a pyrrolopyrimidine derivative that is structurally similar to pemetrexed.
Pemetrexed Impurity A is usually quantified using High-Performance Liquid Chromatography (HPLC) and other analytical techniques. The acceptable limit for Pemetrexed Impurity A in pemetrexed drug substance and drug product is typically set at 0.2% or less.
In conclusion, Pemetrexed Impurity A is an important reference standard used in the manufacturing and testing of pemetrexed, a chemotherapy drug used for the treatment of various types of cancer. Its chemical formula, molecular weight, and structure are important characteristics that need to be monitored to ensure the quality and safety of the drug.
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Related Compounds
Pemetrexed Dimethyl Ester | Pemetrexed Impurity 24 | N-nitroso Pemetrexed | Pemetrexed Nitroso Impurity 2 | Pemetrexed Keto impurity isomers 2 | Pemetrexed Impurity 42 | Pemetrexed Impurity Mixture (Impurities A and D) | N-Methyl Pemetrexed | Pemetrexed-1-methyl Ester | Pemetrexed Monomethyl Ester 2 | Pemetrexed PMT-1 impurity | Pemetrexed Nitroso Impurity 3 | Tris Pemetrexed | Pemetrexed Impurity 33 | Pemetrexed Monomethyl Ester 1 | Pemetrexed EP Impurity D | Pemetrexed EP Impurity E | Pemetrexed Impurity 36 | Pemetrexed Alpha-hydroxy lactum | Pemetrexed Glutamide Impurity | Pemetrexed Disodium – D-Isomer | Pemetrexed Keto impurity di sodium salt | Pemetrexed EP Impurity B | Pemetrexed Alanine Impurity | Pemetrexed EP Impurity B and Impurity C mixture | Pemetrexed Diethyl Ester | Pemetrexed Impurity 20 | Pemetrexed Alpha-hydroxy lactum isomers 2 | Pemetrexed EP Impurity C | Pemetrexed epoxy hemiaminal | Diethyl ((S)-4-amino-5-ethoxy-5-oxopentanoyl)-L-glutamate | Pemetrexed Impurity 29 | Pemetrexed opened Ring keto amide | Pemetrexed Impurity 28 | Pemetrexed Keto impurity (Mixture of isomers) | Pemetrexed Impurity 32 | Pemetrexed disodium Impurity A | Pemetrexed Impurity 2 |