Ribociclib impurity-2

Ribociclib impurity-2 is a chemical compound that is used in the pharmaceutical industry as a reference standard for the detection and quantification of impurities in the active ingredient ribociclib. Ribociclib is a selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6) and is used in the treatment of hormone receptor-positive breast cancer. Ribociclib impurity-2 is a synthetic compound that is chemically related to ribociclib and has a similar structure. It is used as a reference standard in the quality control of ribociclib formulations and is also used in research and development of new drugs. Chemically, ribociclib impurity-2 is a white to off-white solid that is soluble in organic solvents such as methanol, ethanol, and acetonitrile. Its molecular formula is C16H19N5O3 and its molecular weight is 329.36 g/mol. It has a melting point of 165-167°C and a purity of at least 98%. The usage of ribociclib impurity-2 is important in ensuring the safety and efficacy of ribociclib formulations. Impurities in pharmaceutical products can affect their stability, bioavailability, and safety, and therefore it is necessary to monitor and control impurities at every stage of drug development and manufacturing. Ribociclib impurity-2 is a valuable tool in this process, as it enables accurate detection and quantification of impurities in ribociclib formulations.