Ribociclib succinate
| Product Name | Ribociclib succinate |
|---|---|
| Alternate Names | Ribociclib Impurities, Impurities of Ribociclib |
| CAT No. | CS-T-93359 |
| CAS No. | 1374639-75-4 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 552.63 g/mol |
| Mol. For. | C₂₇H₃₆N₈O₅ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Ribociclib |
| Therapeutic | Anti-Cancer / Oncology |
| Smileys | CN(C)C(=O)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5.C(CC(=O)O)C(=O)O |
| Canonical Smiles | CN(C)C(=O)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5.C(CC(=O)O)C(=O)O |
| InchIKey | NHANOMFABJQAAH-UHFFFAOYSA-N |
| Inchl | InChI=1S/C23H30N8O.C4H6O4/c1-29(2)22(32)19-13-16-14-26-23(28-21(16)31(19)17-5-3-4-6-17)27-20-8-7-18(15-25-20)30-11-9-24-10-12-30;5-3(6)1-2-4(7)8/h7-8,13-15,17,24H,3-6,9-12H2,1-2H3,(H,25,26,27,28);1-2H2,(H,5,6)(H,7,8) |
| IUPAC | butanedioic acid;7-cyclopentyl-N,N-dimethyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrrolo[2,3-d]pyrimidine-6-carboxamide |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Ribociclib succinate, also known as Kisqali, is a prescription medication used in the treatment of hormone receptor-positive, HER2-negative advanced breast cancer. It is a selective cyclin-dependent kinase 4/6 (CDK 4/6) inhibitor that works by blocking the activity of CDK 4/6 enzymes, which promote cell division and growth.
Ribociclib succinate is administered orally in tablet form, usually once daily for three weeks followed by one week off. It is recommended to be taken with food to increase its absorption and reduce potential gastrointestinal side effects. The dosage and duration of treatment may vary depending on the individual's medical history and response to the medication.
Chemically, Ribociclib succinate is a salt form of Ribociclib, a pyridine-containing compound. Its empirical formula is C23H30N8O·C4H6O4, and it has a molecular weight of 552.66 g/mol. It is highly soluble in water and ethanol, and its solubility is pH-dependent.
Like all medications, Ribociclib succinate may cause side effects, including fatigue, nausea, vomiting, diarrhea, fever, and decreased appetite. It may also cause more serious side effects, like low white blood cell count, liver problems, and blood clots. It is important for patients to discuss any potential side effects with their healthcare provider and report any new or worsening symptoms immediately.
In summary, Ribociclib succinate is a selective CDK 4/6 inhibitor used in the treatment of advanced breast cancer. It is administered orally in tablet form and may cause various side effects.
Get an Instant Quote
Related Compounds
Ribociclib Succinate Amine impurity | Ribociclib Nitroso Impurity 1 | Ribociclib impurity-10 | Ribociclib Chloro Hydroxymethyl Impurity | Ribociclib N-oxobutanoic acid | Ribociclib impurity-2 | Ribociclib Succinate Amino trityl impurity | Ribociclib Succinate Piperazine amide impurity | Ribociclib Nitroso Impurity 2 | Ribociclib impurity-9 | Ribociclib open ring formamide impurity | Ribociclib ACID IMPURITY | Ribociclib Chloro Amide Impurity | Ribociclib Impurity 12 | Ribociclib Mehyl Ester | Ribociclib Succinate Triphenyl isopropyl ether impurity | Ribociclib Impurity 13 | N-Trityl Ribociclib impurity | Ribociclib N-Oxide | Ribociclib impurity-7 | Ribociclib Impurity 29 | Ribociclib impurity-5 | Ribociclib Nitroso Impurity 3 | N-formyl Ribociclib |