Roflumilast D4

Product Name Roflumilast D4
Alternate Names Roflumilast Stable Isotopes, Stable Isotopes of Roflumilast
CAT No. CS-O-02897
CAS No. 162401-32-3(Unlabeled)
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 407.23 g/mol
Mol. For. C₁₇H₁₀D₄Cl₂F₂N₂O₃
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Roflumilast
Purity 98.64
Therapeutic Anti-Asthma / COPD
Smileys FC(F)OC1=C(C=C(C(NC(C(Cl)=CN=C2)=C2Cl)=O)C=C1)OCC3C([2H])([2H])C3([2H])[2H]
Canonical Smiles C1CC1COC2=C(C=CC(=C2)C(=O)NC3=C(C=NC=C3Cl)Cl)OC(F)F
InchIKey MNDBXUUTURYVHR-UHFFFAOYSA-N
Inchl InChI=1S/C17H14Cl2F2N2O3/c18-11-6-22-7-12(19)15(11)23-16(24)10-3-4-13(26-17(20)21)14(5-10)25-8-9-1-2-9/h3-7,9,17H,1-2,8H2,(H,22,23,24)
IUPAC 3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
Controlled No
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Roflumilast D4 is a deuterated version of the drug Roflumilast, which is a phosphodiesterase 4 (PDE4) inhibitor. This medication is used to treat chronic obstructive pulmonary disease (COPD) in patients with a history of severe exacerbations. COPD is a progressive lung disease characterized by inflammation and narrowing of the airways, leading to breathing difficulties and reduced lung function. Roflumilast D4 works by reducing inflammation in the lungs, which helps to improve breathing and reduce the risk of exacerbations. It is believed to do this by inhibiting the activity of PDE4, an enzyme that is involved in the production of inflammatory molecules in the body. Chemically, Roflumilast D4 is a deuterated version of Roflumilast, meaning that it contains deuterium atoms in place of some of the hydrogen atoms in the molecule. Deuterium is a stable isotope of hydrogen that has a slightly greater mass, which can affect the way that the drug is metabolized in the body. This modification can increase the half-life of the drug, which may improve its effectiveness and reduce the frequency of dosing required. In summary, Roflumilast D4 is a medication used to treat COPD by reducing inflammation in the lungs. It is a deuterated version of Roflumilast, which may improve its pharmacokinetic properties.

Related Compounds

Roflumilast N-oxide D4 | Roflumilast Dimer-D8 |

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