Product Detail
tert-Butyl-4-hydroxy Atorvastatin-d5
Stable Isotopes
Stock Status: Enquire
Live
For Research & Analytical Purposes. Not for Personal use.
Category
Stable Isotopes
API Family
--
Storage
Refer MSDS for complete information.
Hazard Information
Refer MSDS for complete information.
tert-Butyl-4-hydroxy Atorvastatin-d5 Product Information
tert-Butyl-4-hydroxy Atorvastatin-d5 is listed under Stable Isotopes. It is associated with and is intended for analytical research, quality control and pharmaceutical reference standard applications. The product is supplied by Clearsynth under CAT No. CS-T-100712.
Clearsynth provides this compound for research and analytical use, with product information including CAS number, molecular formula, molecular weight, stock enquiry details and supporting documentation.
Technical Data
Product Name
tert-Butyl-4-hydroxy Atorvastatin-d5
CAS No.
-
CAT No.
CS-T-100712
Molecular Formula
C37H38D5FN2O6
Molecular Weight
635.78
Category
Storage Condition
Refer MSDS for complete information.
IUPAC Name
tert-Butyl-4-hydroxy Atorvastatin-d5
Hazard Compound
Refer MSDS for complete information.
Description
Overview
"tert-Butyl-4-hydroxy Atorvastatin-d5 is the labeled analogue of tert-Butyl-4-hydroxy Atorvastatin (B692345), an intermediate in the synthesis of 4-Hydroxy Atorvastatin Hemicalcium Salt (H828961), a hydroxylated metabolite of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia."
Synonyms
"(3R,5R)-tert-Butyl 7-(2-(4-Fluorophenyl)-4-((4-hydroxyphenyl)carbamoyl)-5-isopropyl-3-phenyl-d5-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate"
Application Notes
"tert-Butyl-4-hydroxy Atorvastatin-d5 is the labeled analogue of tert-Butyl-4-hydroxy Atorvastatin (B692345), an intermediate in the synthesis of 4-Hydroxy Atorvastatin Hemicalcium Salt (H828961), a hydroxylated metabolite of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia."
References
"Smith, S. et al.: Am. J. Cardiol., 80, 10H (1997); Jacobsen, W. et al.: Drug Metab. Dispos., 28, 1369 (2000); Istvan, E. et al.: Science, 292, 1160 (2001); Tabernero, L. et al.: J. Biol. Chem., 278, 19933 (2003); Bratton, L. et al.: Bioorg. Med. Chem., 15"
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