Tetra acetyl Dapagliflozin

Product Name Tetra acetyl Dapagliflozin
Alternate Names Dapagliflozin Impurities, Impurities of Dapagliflozin
CAT No. CS-O-14895
CAS No. 461432-25-7
Category Impurities
Stock IN-Stock
Mol. Wt. 577.02 g/mol
Mol. For. C₂₉H₃₃ClO₁₀
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Dapagliflozin
Purity 95%
Therapeutic Anti-Diabetic
Smileys CCOC1=CC=C(C=C1)CC2=CC([C@@H]3[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O3)=CC=C2Cl
Canonical Smiles CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C3C(C(C(C(O3)COC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C)Cl
InchIKey DKOQYKRDCDCNOR-ZCCUTQAASA-N
Inchl InChI=1S/C29H33ClO10/c1-6-35-23-10-7-20(8-11-23)13-22-14-21(9-12-24(22)30)26-28(38-18(4)33)29(39-19(5)34)27(37-17(3)32)25(40-26)15-36-16(2)31/h7-12,14,25-29H,6,13,15H2,1-5H3/t25-,26+,27-,28+,29+/m1/s1
IUPAC [(2R,3R,4R,5S,6S)-3,4,5-triacetyloxy-6-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]oxan-2-yl]methyl acetate
Controlled No
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Tetra acetyl Dapagliflozin is a synthetic compound that belongs to the class of sodium-glucose cotransporter 2 (SGLT2) inhibitors. It is a prodrug of dapagliflozin, which is used to treat type 2 diabetes mellitus. The tetra acetylation of dapagliflozin increases its solubility and bioavailability, making it more effective than dapagliflozin alone. Tetra acetyl Dapagliflozin works by inhibiting the SGLT2 transporter in the kidneys, which is responsible for reabsorbing glucose from the urine back into the bloodstream. By inhibiting this transporter, the drug increases the amount of glucose excreted in the urine, leading to a decrease in blood glucose levels. The chemical formula of Tetra acetyl Dapagliflozin is C25H30O10, with a molecular weight of 490.50 g/mol. It is a white to off-white crystalline powder that is soluble in water, ethanol, and dimethyl sulfoxide. Tetra acetyl Dapagliflozin is administered orally as a tablet, with a recommended dose of 10 mg once daily. The drug is metabolized in the liver and excreted in the urine, with a half-life of approximately 12 hours. Overall, Tetra acetyl Dapagliflozin is a safe and effective drug for the management of type 2 diabetes mellitus, with a low risk of adverse effects. However, it should be used with caution in patients with renal impairment or dehydration, as it may increase the risk of kidney injury.

Related Compounds

Dapagliflozin Bromo impurity D5 | Dapagliflozin Diproline | Dapagliflozin Impurity 13 | MonoAcetyl Dapagliflozin | Dapagliflozin 5-Acetyl impurity | Dapagliflozin Impurity 5 (Mixture of Diastereomers) | Dapagliflozin Impurity 47 | Desethyl alpha-Dapagliflozin impurrity | Dapagliflozin Impurity 27 | Dapagliflozin Impurity 8 | Dapagliflozin Impurity 19 | Dapagliflozin Allose Isomer | Dapagliflozin Open Ring | Dapagliflozin Impurity 17 | Dapagliflozin Bromo lactone impurity | Dapagliflozin Impurity 38 | N- butyl dapagliflozin impurity | Dapagliflozin 4-bromo tetraacetate impurity | Dapagliflozin Dimer Impurity | fluoro-Dapagliflozin | Dapagliflozin Impurity 21 | Dapagliflozin Enantiomer butane-1,2-diol hydrate | Dapagliflozin Impurity 37 | Dapagliflozin Imp.-S2E (Tri acetylated) | Peroxide dapagliflozin impurity | Dapagliflozin C2 Epimer | Dapagliflozin methoxy furanose Impurity | Dapagliflozin Impurity 9 | Des Chloro Dapagliflozin | Dapagliflozin Impurity 16 | Dapagliflozin Alpha isomer tetraacetate | Dapagliflozin Sugar Dimer | Dapagliflozin furanose sugar dimer | Dapagliflozin Impurity 3 | Ena-Dapagliflozin butane-1,2-diol hydrate | Dapagliflozin 4-chloro phenyl Dimer impurity | Desglucuronide(2S)Dapagliflozin Dimer | Dapagliflozin Impurity 21 | Dapagliflozin methoxy pyranose impurity | Dapagliflozin Dimer-1 | Dapagliflozin Impurity 24 | Dapagliflozin (RS) Furanose | Dapagliflozin des-ethoxy impurity | Dapagliflozin Impurity 30 | Dapagliflozin Impurity 12 | C2 epimer of Methoxy Dapagliflozin impurity | Dapagliflozin Impurity 1 | Dapagliflozin Deschloro tetraacetate impurity | Dapagliflozin Impurity 35 | Dapagliflozin TNG | Dapagliflozin Impurity 64 | Dapagliflozin Impurity S3A | Dapagliflozin Hydroxy Impurity | Dapagliflozin Dimer Impurity | Dapagliflozin Impurity 23 | Dapagliflozin 3-Acetyl imurity | Dapagliflozin Impurity 2 | Dapagliflozin-(RRS)-Furanose isomer | Dapagliflozin Dimethoxy impurity | Desglucuronide Dapagliflozin Dimer | Dapagliflozin Impurity 14 | Dapagliflozin Impurity 25 | Dapagliflozin 4-Acetyl imurity | Dapagliflozin Impurity B | Dapagliflozin Impurity 6 | Dapagliflozin-(R)-Furanose |

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