Tetrahydrofolic acid 13C5

[13C5]-Tetrahydrofolic acid (THF) is a stable isotope-labeled form of the vitamin folic acid, used in medical research and diagnosis. THF plays a crucial role in the synthesis of nucleic acids and amino acids, making it essential for cell growth and division. It is also important for the formation of red blood cells and the maintenance of healthy skin, hair, and nails. The labeled carbon atoms in [13C5]-THF are useful for tracking the metabolism and distribution of folic acid in the body. Researchers can use it to study the absorption, distribution, and excretion of folic acid in healthy individuals or those with certain medical conditions. It can also be used in the diagnosis of certain types of anemia and cancer. Chemically, [13C5]-THF is a complex molecule with a molecular weight of 463.5 g/mol. It contains a pteridine ring, a para-aminobenzoic acid (PABA) moiety, and a glutamic acid residue, among other functional groups. The labeled carbon atoms are located in the pteridine ring and the glutamic acid side chain. [13C5]-THF is typically administered intravenously or orally in clinical studies. It is generally well-tolerated, with few side effects reported. However, as with any medication, individuals should consult with their healthcare provider before using [13C5]-THF.