Tetrahydrofolic acid 13C6

[13C6]-Tetrahydrofolic acid is a stable isotope-labeled form of tetrahydrofolic acid, which is an important coenzyme involved in one-carbon metabolism and DNA synthesis. It is a member of the folate family of vitamins, and is essential for the growth and proliferation of cells. [13C6]-Tetrahydrofolic acid is synthesized from the amino acid histidine and is converted into various active forms such as 5,10-methylene-tetrahydrofolic acid and 5-methyl-tetrahydrofolic acid. [13C6]-Tetrahydrofolic acid is used extensively in biochemical and medical research, particularly in studies involving one-carbon metabolism, DNA synthesis, and folate metabolism. It is used to study the pathways of folate metabolism, and to investigate the role of folate in various diseases such as cancer and neural tube defects. It is also used in clinical settings to diagnose and monitor folate deficiency, which can lead to anemia, birth defects, and other health conditions. Chemically, [13C6]-Tetrahydrofolic acid is a stable isotope-labeled compound, which means that six of the carbon atoms in the molecule are replaced with the heavier isotope carbon-13. This labeling allows for the precise tracking of the molecule in metabolic studies, and can help to distinguish it from other compounds in complex biological samples. The chemical properties of [13C6]-Tetrahydrofolic acid are similar to those of the unlabeled molecule, and it can be synthesized using similar methods.