Tofacitinib Impurity 6

Tofacitinib Impurity 6 is a chemical compound that is commonly used in the pharmaceutical industry as a reference standard for the analysis of tofacitinib, a drug used to treat rheumatoid arthritis and psoriasis. This impurity is also known as 3-[(3R,4R)-4-methyl-3-(methylsulfonyl)piperazin-1-yl]pyridine, and it is a white to off-white powder with a molecular weight of 312.4 g/mol. The usage of Tofacitinib Impurity 6 is predominantly focused on analytical testing and quality control in the pharmaceutical manufacturing process. It is used as a reference standard for the identification and quantification of tofacitinib impurities in drug substances and drug products. Tofacitinib Impurity 6 is also used to establish the purity and potency of tofacitinib during the development and production of the drug. In terms of chemical information, Tofacitinib Impurity 6 is a piperazine derivative with a pyridine ring. It is a chiral molecule with two stereoisomers, and the (3R,4R) isomer is the active form. This impurity is not expected to have any pharmacological activity and is considered to be a non-toxic substance. Overall, Tofacitinib Impurity 6 plays an essential role in ensuring the quality and safety of tofacitinib, which is a critical drug used to treat autoimmune diseases. Its reference standard is a necessary tool in the pharmaceutical industry for the accurate analysis of tofacitinib and its impurities.