CAS No.
[519-02-8(Unlabelled)]
Storage Condition
Refer MSDS for complete information
Synonyms
(+)-Matrine-d3, 519-02-8(Unlabelled)
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
(+)-Matrine-d3 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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(+)-Matrine-d3 usage and description
(+)-Matrine-d3 is a deuterated form of the natural alkaloid (+)-Matrine. It is a potent and selective inhibitor of the human immunodeficiency virus (HIV) and has been extensively studied for its anti-viral and anti-cancer effects.
The chemical formula of (+)-Matrine-d3 is C15H15D3NO, with a molecular weight of 232.32 g/mol. The deuterated form of (+)-Matrine is created by replacing three hydrogen atoms in the molecule with deuterium atoms, resulting in a heavier molecule that is ideal for use in isotopic labeling studies.
The usage of (+)-Matrine-d3 is primarily in pharmacological research, where it is used as a tool compound to investigate the mechanism of action of the non-deuterated form of (+)-Matrine. It is also used in metabolic labeling studies to track the metabolic fate of the natural alkaloid in biological systems.
The anti-viral and anti-cancer effects of (+)-Matrine-d3 are believed to be due to its ability to inhibit the activity of several enzymes, including reverse transcriptase and protease, which are essential for HIV replication and cancer cell growth. Additionally, (+)-Matrine-d3 has been shown to have anti-inflammatory and immunomodulatory properties, making it a promising compound for the treatment of a variety of diseases.
In summary, (+)-Matrine-d3 is a deuterated form of the natural alkaloid (+)-Matrine, primarily used in pharmacological research to investigate the mechanism of action and metabolic fate of the non-deuterated form. It has potent anti-viral, anti-cancer, anti-inflammatory, and immunomodulatory effects and is a promising compound for the treatment of a variety of diseases.
