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CAS No.
-
Product Code
CS-T-96288
M.F.
C11H11D3O2S
M.W.
213.31
Category
Stable Isotopes
Storage Condition
Refer MSDS for complete information.
IUPAC Name
(R)-(+)-Thiolactomycin-d3
References
"Kapilashrami, K., et al.: J. Biol. Chem., 288, 6045 (2013); Paneerselvam, V., et al.: J. Pharm. Res., 4, 4618 (2011); Katane, M., et al.: Biochimie, 92, 1371 (2010)"
(R)-(+)-Thiolactomycin-d3 is the isotope labelled analog of (R)-(+)-Thiolactomycin (T350880); a natural product inhibitor of ß-Ketoacyl-AcpM Synthase A (KasA). It inhibits the synthesis of mycolic acid which is a major cell wall component of Mycobacterium tuberculosis. Also an inhibitor of D-Aspartate oxidase (DDO).
Hazard Compound
Refer MSDS for complete information.
Overview
(R)-(+)-Thiolactomycin-d3 is the isotope labelled analog of (R)-(+)-Thiolactomycin (T350880); a natural product inhibitor of ß-Ketoacyl-AcpM Synthase A (KasA). It inhibits the synthesis of mycolic acid which is a major cell wall component of Mycobacterium tuberculosis. Also an inhibitor of D-Aspartate oxidase (DDO).