Therapeutic Uses
Anticonvulsants (Anti-Epileptics)
Storage Condition
Store at freezer (-20°C) for long term storage
Synonyms
(S)-4-Hydroxy Mephenytoin, 82695-93-0
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Yes -Refer MSDS for accurate information
(S)-4-Hydroxy Mephenytoin is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
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(S)-4-Hydroxy Mephenytoin usage and description
(S)-4-Hydroxy Mephenytoin is a chemical compound that belongs to the class of anticonvulsants, a group of drugs used to treat epilepsy and other seizure disorders. It is specifically used as a metabolite of mephenytoin, another anticonvulsant drug. (S)-4-Hydroxy Mephenytoin is a chiral molecule, meaning it has two mirror-image forms or enantiomers. The (S)-enantiomer is the active form of the compound, while the inactive (R)-enantiomer is eliminated from the body through metabolism.
The chemical structure of (S)-4-Hydroxy Mephenytoin contains a hydroxyl group (-OH) attached to a phenyl ring. It is produced in the liver by the enzyme CYP2C19, which is responsible for the metabolism of mephenytoin. The concentration of (S)-4-Hydroxy Mephenytoin in the blood is used as a marker for CYP2C19 activity, which varies widely among individuals due to genetic differences.
Clinical studies have shown that (S)-4-Hydroxy Mephenytoin has anticonvulsant properties similar to those of mephenytoin. It has also been investigated for its potential use as a biomarker for drug interactions and personalized medicine. However, its use as a therapeutic agent is limited due to its short half-life and rapid elimination from the body. Nevertheless, (S)-4-Hydroxy Mephenytoin remains an important tool in pharmacogenetic research and drug development.
