Reference Standard Product Detail

11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one-d2

Name: 11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one-d2
Brand: Clearsynth
SKU: CS-T-96411
Availability: LimitedAvailability

Explore technical data, documentation access, molecular information and enquiry options for this Clearsynth research product.

Product Code: CS-T-96411 Reference Standard Research Use Only

11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one-d2

Reference Standard

Stock Status: : Enquire Live

CAT No.

CS-T-96411

CAS No.

Molecular Formula

C₁₅H₁₂D₂N₄O₂

Molecular Weight

284.31

There is no hazardous surcharge associated with this product.

There is no packaging charge associated with this product.

For Research Purposes only. Not for Personal or Veterinary use.

All compounds supplied are strictly intended for laboratory, research, analytical, and scientific use only. They are not meant for human consumption, therapeutic use, or any form of clinical application.

CAS No.

Product Code

CS-T-96411

M.F.

C₁₅H₁₂D₂N₄O₂

M.W.

284.31

Smiles

O=C1C2=CC=CN=C2N(C3CC3)C4=NC=CC(C([2H])([2H])O)=C4N1

Category

Reference Standard

API Family

Storage Condition

Refer MSDS for complete information.

IUPAC Name

11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one-d2

References

"Hargrave, K.D., et al.: J. Med. Chem., 34, 2231 (1991); Cheeseman, S.H., et al.: Antimicrob. Agents Chemother., 37, 178 (1993); Guay, L.A., et al.: Lancet, 354, 795 (1999)"

Synonyms

11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one-d2

Application Notes

"11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one-d2 is a labelled analogue of 11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one (C988365), which is a metabolite of Nevirapine (N391275), which is a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. It is also an antiviral.11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one-d2 is also an intermediate in synthesizing Nevirapine-d2 (N391276), an isotope labelled Nevirapine (N391275), which acts as a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. Antiviral."

Hazard Compound

Refer MSDS for complete information.

Overview

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11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one-d2

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11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one-d2

11-Cyclopropyl-5,11-dihydro-4-(hydroxymethyl)-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one-d2

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