Storage Condition
Refer MSDS for complete information
Synonyms
2-Deoxyuridine-3 13C, 478510-89-3
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
2-Deoxyuridine-3 13C is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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2-Deoxyuridine-3 13C usage and description
2-Deoxyuridine-3 13C is a stable isotope-labeled nucleoside that is widely used in biochemical research. It is a modified form of thymidine that contains a carbon-13 isotope in the third position of the deoxyribose sugar. This stable isotope labeling allows for precise tracking and analysis of nucleotide metabolism in living cells.
2-Deoxyuridine-3 13C is commonly used in DNA replication studies, as it is incorporated into newly synthesized DNA strands during cell division. This allows researchers to follow the fate and turnover of DNA within cells, as well as to study the mechanisms of DNA damage and repair.
In addition to its use in DNA replication studies, 2-Deoxyuridine-3 13C is also used in cancer research. Cancer cells frequently exhibit altered nucleotide metabolism, and the use of stable isotope labeling can help researchers to better understand these metabolic changes and develop new therapeutic strategies.
From a chemical standpoint, 2-Deoxyuridine-3 13C is a nucleoside composed of a deoxyribose sugar, a nitrogenous base (uracil), and a carbon-13 isotope. It is typically synthesized using a combination of chemical and enzymatic methods, and is available commercially from a variety of sources. Its stable isotope labeling makes it a powerful tool for studying nucleotide metabolism and DNA replication in living cells.
