CAS No.
[1177-87-3(Unlabelled)]
Storage Condition
Refer MSDS for complete information
Synonyms
(11β,16α)-21-(Acetyloxy)-9-fluoro-11,17-dihydroxy-16-methyl-pregna-1,4-diene-3,20-dione-d5; 9-Fluoro-11β,17,21-trihydroxy-16α-methyl-pregna-1,4-diene-3,20-dione 21-Acetate-d5; Decadronal-d5; Dectancyl-d5; Dex-Cortidelt Acetate-d5; Dexa-Cortisyl-d5; NSC 39471-d5
Application Notes
Useful research chemical for a range of applications
Hazard Compound
Refer MSDS for complete information
21-O-Acetyl Dexamethasone-d5 is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
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21-O-Acetyl Dexamethasone-d5 usage and description
21-O-Acetyl Dexamethasone-d5 is a deuterated analogue of 21-O-Acetyl Dexamethasone, which is a synthetic glucocorticoid used as an anti-inflammatory and immunosuppressive agent. It is commonly used to treat conditions such as allergies, asthma, rheumatoid arthritis, and skin disorders.
The deuterated form, 21-O-Acetyl Dexamethasone-d5, is used in research and clinical studies to track the metabolism and distribution of the drug in the body. Deuterium, a stable isotope of hydrogen, is used as a tracer to label the drug molecule, allowing researchers to determine the location and concentration of the drug in various tissues and organs. This information can be used to optimize dosing regimens and improve treatment outcomes.
Chemically, 21-O-Acetyl Dexamethasone-d5 is a white crystalline powder with a molecular formula of C24H29D5O6. It has a molecular weight of 433.59 g/mol and a melting point of 262-264°C. The drug is soluble in organic solvents such as ethanol and chloroform, but has limited solubility in water.
In conclusion, 21-O-Acetyl Dexamethasone-d5 is a useful tool for studying the pharmacokinetics and pharmacodynamics of 21-O-Acetyl Dexamethasone. Its deuterated form allows for precise tracking of the drug in the body, providing valuable information for drug development and clinical use.
