Storage Condition
Store at freezer (-20°C) for long term storage
Synonyms
Calcipotriol EP Impurity D
Application Notes
Useful research chemical for a range of applications
Purity by HPLC
Not less than 90%
Hazard Compound
No -Refer MSDS for accurate information
24-Epi-Calcipotriol is a drug product that is used as an analytical standard for HPLC, as well as in research and development of drugs.
Refund Policy
We are committed to offering products of the highest quality in order to meet the needs of our customers, and have elaborate systems in
place to ensure that material specifications, their certification and all handling and storage conditions are communicated at the time of
material handover.
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While we will always address product issues after the 45 day return window has passed, we cannot issue a refund or account credit. As
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24-Epi-Calcipotriol usage and description
24-Epi-Calcipotriol is a synthetic derivative of Vitamin D3 and acts as an analog of calcitriol. It is primarily used in the treatment of psoriasis, a chronic autoimmune skin disorder. The compound works by binding to Vitamin D receptors on skin cells, thereby regulating the growth and differentiation of these cells.
Research studies have shown that 24-Epi-Calcipotriol has similar efficacy to calcipotriol, a widely used topical medication for psoriasis. However, unlike calcipotriol, 24-Epi-Calcipotriol has a lower risk of inducing hypercalcemia, a condition characterized by elevated levels of calcium in the blood.
Chemically, 24-Epi-Calcipotriol is a highly lipophilic compound with a molecular weight of 412.68 g/mol. Its chemical formula is C27H40O3, and its systematic name is (1R,3S,5Z)-5-{2-[(1R,3aS,7aR)-1-[(2R)-6-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene}-4-methylene-cyclohexane-1,3-diol.
In summary, 24-Epi-Calcipotriol is a promising therapeutic agent for the management of psoriasis due to its potent activity and low risk of adverse effects. However, further clinical trials are needed to establish its safety and efficacy in larger patient populations.
